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EEC217 – Biomedical Electronics

4 units – Spring Quarter

Lecture: 3 hours

Prerequisite: EEC 210 or consent of instructor; special consideration and accommodation will be made for biomedical or signal processing majors who have not taken 210.

Grading: Letter.

Catalog Description:

Circuit design for medical applications including weak inversion amplifiers; integrated ULF filters; chopper stabilitzation; electrochemical interfaces; neurostimulation pulse generation; wireless powering of and communication with implantable devices. Electrophysiological signaling and aspects of signal processing for biomedical systems.

Expanded Course Description:

  1. Introduction
    1. Overview of Applications of Electronics in Medicine: Diagnostics and Therapeutics
    2. Overview of sensing and actuation modalities in biomedical electronics
  2. System Design
    1. Analog vs Digital power consumption
      1. Comparison ADC energy per conversion step with digital gate switching energy
      2. Derivation of rules of thumb for analog/digital partitioning in medical electronics systems
    2. Analog Cochlea vs Digital Cochlea
  3. Signal Acquisition – External and Implanted
    1. Instrumentation Amplifier
    2. Neurosignal Acquisition
      1. Low Power, Low Frequency Filtering Amplifiers
        1. Weak Inversion Operation
        2. Very low Frequency Filtering
        3. Noise Analysis
      2. Low Power, Low Frequency ADCs
    3. Mechanical and Acoustic
      1. Piezoressistive, Accelerometers, Flowmeters
        1. Wheatstone Bridge Sensing
        2. Noise Analsis
        3. S approach – learn from automotive sensors
    4. Electrochemical
      1. Amperometric and Voltametric Biosensors
      2. Case Study:  Potentiostat Design for Glucose Sensor
    5. Hall Effect Based Sensor
  4. Actuation – External and Implanted
    1. Neurostimulation: retinal, cochlear, cardiac, paint therapy, DVS, muscle actuation
      1. Controlled Low Voltage Applications vs High Voltage, less understood applications
      2. Biphasic Stimulation – why and parameters to vary
      3. Charge Pumping
      4. Ramp rate and Duty Cycle Control
    2. Mechanical
      1. Drug Delivery Pump Design and Control Circuitry
    3. Ablation: EM and Acoustic
  5. Power Supply for Implantable Medical Devices
    1. Battery Technology
    2. EM Wireless Power Transfer
      1. Link Deseign
        1. Choise of Operating Frequency
        2. Resonant Tuning Techniques
        3. Simultaneious Conjugate Matching
      2. Transmitter Design
        1. Power Amplifier Design
      3. Receiver Design
        1. Over Voltage Protection Circuits
        2. High Efficiency Low Voltage Rectifiters
    3. Acoustic – brief discussion of recently commercialized technology
    4. Energy Scavenging
      1. Mechanical
        1. Rotary: MEMs generator design: rotor and stator fabrication limits
        2. Vibrational: Cantilever fabrication limits
      2. Thermal
      3. Rectifier Design for these very low energy, vlf generators
      4. Supercapacitor charging circuits
      5. Supercapacitor biocompatibility constraints
  6. Data Communications to and from Implanted Devices
    1. RF wireless
      1. Stand Alone Communication Link
        1. Overview of commonly used modulation schemes
        2. Discussion of why those schemes are used
        3. Circuit Implementation of Best Schemes
      2. Modulated Power Carrier
    2. Tissue as a COnducting Medium
      1. Case Study of Proteus Scheme
    3. Brief Mention of Body Area Network
  7. Case Study: Pacemaker

Textbook/reading: 

  1. Instrumentation by J. Webster and Analysis and Application of Analog Electronic Circuits to Biomedical Instrumentaiton by Northrop will be used as references for characteristics of biosignals.
  2. Analysis and Design of Analog Integrated Circuits by Gray Meyer Hurst and Lewis will be a useful text.
  3. Journal papers will be issued as references for most circuit discuission.

Instructor: O’Driscoll